CD80 insights as therapeutic target in the current and future treatment options of frequent-relapse minimal change disease

• Main Authors: Teh, Yoong Mond, Lim, Soo Kun, Jusoh, Norhana, Osman, Kahar, Mualif, Siti Aisyah
• Format: Article
• Language: English
• Published: Hindawi Limited 2021
• Subjects: Q Science (General); R Medicine (General)
• Online Access: http://eprints.utm.my/id/eprint/95967/1/NorhanaJusoh2021_CD80InsightsasTherapeuticTargetintheCurrentandFuture.pdf; http://eprints.utm.my/id/eprint/95967/; http://dx.doi.org/10.1155/2021/6671552

Minimal change disease (MCD) is the most common cause of idiopathic nephrotic syndrome in children, and it is well known for its multifactorial causes which are the manifestation of the disease. Proteinuria is an early consequence of podocyte injury and a typical sign of kidney disease. Steroid-sens...