Preparation and physicochemical characterization of a diclofenac sodium-dual layer polyvinyl alcohol patch

• Main Authors: Sa’adon, S., Mohamed Ansari, M. N., Abd. Razak, S. I., Anand, J. S., Mat Nayan, N. H., Ismail, A. E., Aslam Khan, M. U., Haider, A.
• Format: Article
• Language: English
• Published: MDPI AG 2021
• Subjects: Q Science (General)
• Online Access: http://eprints.utm.my/id/eprint/94879/1/ShafizahSa%E2%80%99adon2021_PreparationandPhysicochemicalCharacterization.pdf; http://eprints.utm.my/id/eprint/94879/; http://dx.doi.org/10.3390/polym13152459

The aim of this study is to prepare a dual layer polyvinyl (PVA) patch using a combination of electrospinning techniques and cryogelation (freeze-thaw process) then subsequently to investigate the effect of freeze-thaw cycles, nanofiber thickness, and diclofenac sodium (DS) loading on the physicoche...