Comparative drug release investigations for diclofenac sodium drug (DS) by chitosan-based grafted and crosslinked copolymers

• Main Authors: Chopra, Lalita, Thakur, Kamal Kishor, Chohan, Jasgurpreet Singh, Sharma, Shubham, Rushdan, Ahmad Ilyas, M. Asyraf, M. R., Syed Zakaria, Sharifah Zarina
• Format: Article
• Language: English
• Published: MDPI 2022
• Subjects: Q Science (General); TP Chemical technology
• Online Access: http://eprints.utm.my/102923/1/AhmadIlyasRushdan2022_ComparativeDrugReleaseInvestigations.pdf; http://eprints.utm.my/102923/; http://dx.doi.org/10.3390/ma15072404

The hydrogels responding to pH synthesized by graft copolymerization only and then concurrent grafting and crosslinking of monomer N-isopropyl acrylamide (NIPAAM) and binary comonomers acrylamide, acrylic acid and acrylonitrile (AAm, AA and AN) onto chitosan support were explored for the percent upl...