Synthesis, molecular docking, and antimalarial activity of hybrid 4-aminoquinoline-pyrano[2,3-c]pyrazole derivatives
Widespread resistance of Plasmodium falciparum to current artemisinin-based combination therapies necessitate the discovery of new medicines. Pharmacophoric hybridization has become an alternative for drug resistance that lowers the risk of drug–drug adverse interactions. In this study, we synthesiz...
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Main Authors: | Shamsuddin, Mohd. Asyraf, Ali, Amatul Hamizah, Zakaria, Nur Hanis, Mohammat, Mohd. Fazli, Hamzah, Ahmad Sazali, Shaameri, Zurina, Lam, Kok Wai, Lee, Mark Wun Fui, Agustar, Hani Kartini, Mohd. Abd. Razak, Mohd. Ridzuan, Latip, Jalifah, Hassan, Nurul Izzaty |
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Format: | Article |
Language: | English |
Published: |
MDPI
2021
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Subjects: | |
Online Access: | http://eprints.utm.my/id/eprint/94836/1/LeeWunFui2021_SynthesisMolecularDockingandAntimalarial.pdf http://eprints.utm.my/id/eprint/94836/ http://dx.doi.org/10.3390/ph14111174 |
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