The single nucleotide polymorphisms rs11761556 and rs12706832 of the leptin gene are associated with type 2 diabetes mellitus in the Iraqi population

• Main Authors: Musafer, K. N. J., Huyop, F. Z., Ewadh, M. J., Supriyanto, E., Al-Thuwaini, T. M., Al-Shuhaib, M. B. S.
• Format: Article
• Language: English
• Published: Institut za Bioloska Istrazivanja 2021
• Subjects: Q Science (General)
• Online Access: http://eprints.utm.my/id/eprint/94531/1/MusaferKarar2021_TheSingleNucleotidePolymorphisms.pdf; http://eprints.utm.my/id/eprint/94531/; http://dx.doi.org/10.2298/ABS210129005M

This study was conducted to assess the potential association between leptin (LEP) gene polymorphisms and type 2 diabetes mellitus (T2DM) in Iraqi patients. Genomic DNA was extracted from 120 diabetic subjects and 100 controls. Three specific PCR fragments were designed to flank three highly frequent...