2-Benzyloxynaphthalene aminoalkylated chalcone designed as acetylcholinesterase inhibitor: structural characterisation, in vitro biological activity and molecular docking studies
The design of an acetylcholinesterase inhibitor with multifunctional properties became the perspective for the development of an effective drug against Alzheimer's disease. Towards this target, 1-{4-hydroxy-3-[(piperidin-1-yl)methyl]phenyl}ethan-1-one (chalcone 3) was prepared and studied as an...
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Main Authors: | , , , , , , , |
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Format: | Article |
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Elsevier B.V.
2020
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Subjects: | |
Online Access: | http://eprints.utm.my/id/eprint/92899/ http://dx.doi.org/10.1016/j.molstruc.2020.128898 |
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