Investigation of acyclovir-loaded, acrylamide-based hydrogels for potential use as vaginal ring

• Main Authors: Sabbagh, Farzaneh, Muhamad, Ida Idayu, Nazari, Zahra, Mobini, Peyman, Mahmoudi Khatir, Nadia
• Format: Article
• Published: Elsevier Ltd. 2018
• Subjects: TP Chemical technology
• Online Access: http://eprints.utm.my/id/eprint/84090/; https://doi.org/10.1016/j.mtcomm.2018.06.010

In the current research, based on the investigation of the drug-loaded hydrogels, the maximum content of acyclovir loading in polymer consequently relates to the pH at which the nanoprecipitation is performed: 24.32% at pH 7.5. The efficiency of loading that corresponds to the percentage of acyclovi...