Trastuzumab-decorated nanoparticles for: In vitro and in vivo tumor-targeting hyperthermia of HER2+ breast cancer

• Main Authors: Hamzehalipour Almaki, J., Nasiri, R., Idris, A., Nasiri, M., Abdul Majid, F. A., Losic, D.
• Format: Article
• Published: Royal Society of Chemistry 2017
• Subjects: TP Chemical technology
• Online Access: http://eprints.utm.my/id/eprint/76467/; https://dx.doi.org/10.1039/C7TB01305A

In this study, a magnetic core-shell modified tumor-targeting nanocarrier (MNPs-PEG-TRA) was engineered and demonstrated for the efficient in vitro and in vivo hyperthermia treatment of breast cancer. Magnetic nanoparticles were used as the initial nanocarriers and modified via PEGylation followed b...