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Anti-inflammatory activities of cucurbitacin E isolated from citrullus latus var. citroides: role of reactive nitrogen species and cyclooxygese enzyme inhibition

The in vivo and in vitro mechanistic anti-inflammatory actions of cucurbitacin E (CE) (Citrullus lanatus var. citroides) were examined. The results showed that LPS/INF-? increased NO production in RAW264.7 macrophages, whereas L-NAME and CE curtailed it. CE did not reveal any cytotoxicity on RAW264....

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Bibliographic Details
Main Authors: Abdelwahab, Siddig Ibrahim, Ahmed Hassan, Loiy Elsir, Mohd. Sirat, Hasnah, Ahmed Yagi, Sakina M., Koko, Waleed S., Mohan, Syam, Taha, Manal Mohamed Elhassan, Ahmad, Syahida, Cheah, Shiau Chuen, Narrima, Putri, Rais, Mohd. Mustafa, A. Hadi, A. Hamid
Format: Article
Published: Elsevier BV 2011
Subjects:
QD Chemistry
Online Access:http://eprints.utm.my/id/eprint/44741/
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http://eprints.utm.my/id/eprint/44741/

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