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Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: a review of common approaches

In this reiew, we have discussed about approaches in pathway based microarray analysis. Commonly, there are two approaches in pathway based analysis, Enrichment Score and Supervised Machine Learning. These pathway based approaches usually aim to statistically define significant pathways that related...

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Main Authors: Misman, Muhammad Faiz, Deris, Safaai, Mohd. Hashim, Siti Zaiton, Jumali, R., Mohamad, Mohd. Saberi
Format: Book Section
Published: Institute of Electrical and Electronics Engineers 2009
Subjects:
QA75 Electronic computers. Computer science
Online Access:http://eprints.utm.my/id/eprint/13040/
http://dx.doi.org/10.1109/ICIME.2009.103
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spelling my.utm.130402017-10-04T07:37:24Z http://eprints.utm.my/id/eprint/13040/ Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: a review of common approaches Misman, Muhammad Faiz Deris, Safaai Mohd. Hashim, Siti Zaiton Jumali, R. Mohamad, Mohd. Saberi QA75 Electronic computers. Computer science In this reiew, we have discussed about approaches in pathway based microarray analysis. Commonly, there are two approaches in pathway based analysis, Enrichment Score and Supervised Machine Learning. These pathway based approaches usually aim to statistically define significant pathways that related to phenotypes of interest. Firstly we discussed an overview of pathway based microarray analysis and its general flow processes in scoring the pathways, the methods applied in both approaches, advantages and limitations based on current researches, and pathways database used in pathway analysis. This review aim to provide better understanding about pathway based microarray analysis and its approaches. Institute of Electrical and Electronics Engineers 2009 Book Section PeerReviewed Misman, Muhammad Faiz and Deris, Safaai and Mohd. Hashim, Siti Zaiton and Jumali, R. and Mohamad, Mohd. Saberi (2009) Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: a review of common approaches. In: Proceedings - 2009 International Conference on Information Management and Engineering, ICIME 2009. Institute of Electrical and Electronics Engineers, New York, 496 -500. ISBN 978-076953595-1 http://dx.doi.org/10.1109/ICIME.2009.103 doi:10.1109/ICIME.2009.103
institution Universiti Teknologi Malaysia
building UTM Library
collection Institutional Repository
continent Asia
country Malaysia
content_provider Universiti Teknologi Malaysia
content_source UTM Institutional Repository
url_provider http://eprints.utm.my/
topic QA75 Electronic computers. Computer science
spellingShingle QA75 Electronic computers. Computer science
Misman, Muhammad Faiz
Deris, Safaai
Mohd. Hashim, Siti Zaiton
Jumali, R.
Mohamad, Mohd. Saberi
Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: a review of common approaches
description In this reiew, we have discussed about approaches in pathway based microarray analysis. Commonly, there are two approaches in pathway based analysis, Enrichment Score and Supervised Machine Learning. These pathway based approaches usually aim to statistically define significant pathways that related to phenotypes of interest. Firstly we discussed an overview of pathway based microarray analysis and its general flow processes in scoring the pathways, the methods applied in both approaches, advantages and limitations based on current researches, and pathways database used in pathway analysis. This review aim to provide better understanding about pathway based microarray analysis and its approaches.
format Book Section
author Misman, Muhammad Faiz
Deris, Safaai
Mohd. Hashim, Siti Zaiton
Jumali, R.
Mohamad, Mohd. Saberi
author_facet Misman, Muhammad Faiz
Deris, Safaai
Mohd. Hashim, Siti Zaiton
Jumali, R.
Mohamad, Mohd. Saberi
author_sort Misman, Muhammad Faiz
title Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: a review of common approaches
title_short Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: a review of common approaches
title_full Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: a review of common approaches
title_fullStr Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: a review of common approaches
title_full_unstemmed Pathway-based microarray analysis for defining statistical significant phenotype-related pathways: a review of common approaches
title_sort pathway-based microarray analysis for defining statistical significant phenotype-related pathways: a review of common approaches
publisher Institute of Electrical and Electronics Engineers
publishDate 2009
url http://eprints.utm.my/id/eprint/13040/
http://dx.doi.org/10.1109/ICIME.2009.103
_version_ 1643646102191210496
score 13.18916

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