A hybrid of SVM and SCAD with group-specific tuning parameter for pathway-based microarray analysis

• Main Authors: Misman, Muhammad Faiz, Mohammad, Mohd. Saber, Deris, Safaai, Raja Mohamad, Raja Nurul Mardhiah, Mohd. Hashim, Siti Zaiton, Omatu, Sigeru
• Format: Book Section
• Published: IEEE 2012
• Subjects: TJ Mechanical engineering and machinery
• Online Access: http://eprints.utm.my/id/eprint/33958/; http://dx.doi.org/10.1007/978-3-642-28765-7_46

The incorporation of pathway data into the microarray analysis had lead to a new era in advance understanding of biological processes. However, this advancement is limited by the two issues in quality of pathway data. First, the pathway data are usually made from the biological context free, when it...