Immobilization of blood coagulant factor VII on polycaprolactone membrane through polydopamine grafting

• Main Authors: Gopal, Rathosivan, Md Shakhih, Muhammad Faiz, Sahalan, Mariaulpa, Lee, Te Chuan, Hermawan, Hendra, Sivalingam, Sivakumar, Kadiman, Suhaini, Saidin, Syafiqah
• Format: Article
• Language: English
• Published: Elsevier 2023
• Subjects: R855-855.5 Medical technology
• Online Access: http://eprints.uthm.edu.my/11660/1/J16187_a1d83041e2470ffe3771a93396a5cc32.pdf; http://eprints.uthm.edu.my/11660/; https://doi.org/10.1016/j.colsurfb.2023.113390

Postoperative bleeding following cardiac surgeries is still an issue that deranges the medical resources and cost. The oral and injection administrations of blood coagulation protein, Factor VII (FVII), is effective to stop the bleeding. However, its short half-life has limited the effectiveness of...