A Potential Epigenetic Marker Mediating Serum Folate and Vitamin B12 Levels Contributes to the Risk of Ischemic Stroke

• Main Authors: Loo, Keat Wei, Heidi, Sutherland, Au, Anthony, Camilleri, Emily, Haupt, Larisa M., Siew, Hua Gan, Griffiths, Lyn R.
• Format: Article
• Language: English
• Published: Hindawi Publishing Corporation 2015
• Subjects: R Medicine (General)
• Online Access: http://eprints.usm.my/38095/1/A_Potential_Epigenetic_Marker_Mediating_Serum_Folate_and_Vitamin_B12_Levels_Contributes_to_the.pdf; http://eprints.usm.my/38095/; http://dx.doi.org/10.1155/2015/167976

Stroke is a multifactorial disease that may be associated with aberrant DNA methylation profiles. We investigated epigenetic dysregulation for themethylenetetrahydrofolate reductase (MTHFR) gene among ischemic stroke patients. Cases and controls were recruited after obtaining signed written inform...