3,5-Bis(arylidene)-4-piperidonesaspotential dengue proteaseinhibitors
Dengue isaseveremosquito-borneviralinfectioncausinghalfamilliondeathsannually. Dengue virusNS2B/NS3proteaseisavalidatedtargetforanti-denguedrugdesign.Aseriesofhitherto unreported 3,5-bis(arylidene)-4-piperidonesanalogues 4a–4j were synthesizedandscreened in silico against DENV2NS2B/NS3proteasetoe...
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Main Authors: | Osman, Hasnah, Idris, Nor Hashima, Kamarulzaman, Ezatul Ezleen, A.Wahab, Habibah, Hassan, Mohd. Zaheen |
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Format: | Article |
Published: |
Elsevier
2017
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Subjects: | |
Online Access: | http://eprints.usm.my/36660/ http://dx.doi.org/10.1016/j.apsb.2017.04.009 |
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