Identification of curcumin analogues with anti-seizure potential in vivo using chemical and genetic zebrafish larva seizure models
Seizures are the outward manifestation of abnormally excessive or synchronous brain activity. While seizures can be somewhat symptomatically managed with anti-epileptic drugs (AEDs), many patients are still refractory to the currently available AEDs. As a result, there is a need to identify new mole...
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Main Authors: | Choo, Brandon Kar Meng, Kundap, Uday Praful, Mohd Faudzi, Siti Munirah, Abas, Faridah, Shaikh, Mohd Farooq, Samarut, Éric |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021
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Online Access: | http://psasir.upm.edu.my/id/eprint/97598/1/ABSTRACT.pdf http://psasir.upm.edu.my/id/eprint/97598/ https://www.sciencedirect.com/science/article/pii/S0753332221008180#:~:text=Complementary%20behavioral%20and%20brain%20seizure%20assays%20in%20zebrafish,screening%20pipeline%20identified%20two%20that%20have%20anti-seizure%20effects. |
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