Assessing the influence of neglected GC-FID variables on the multiple responses using multivariate optimization for the determination of ethanol and acetonitrile in radiopharmaceuticals

• Main Authors: Hassan, Hishar, Othman, Muhammad Faiz, Zakaria, Zainul Amiruddin, Ahmad Saad, Fathinul Fikri, Abdul Razak, Hairil Rashmizal
• Format: Article
• Published: Springer 2021
• Online Access: http://psasir.upm.edu.my/id/eprint/96070/; https://link.springer.com/article/10.1007/s42452-021-04246-8

Analytical gas chromatography in line with a flame ionization detector (GC-FID) method was developed and validated for direct determination of organic solvents in [18F]fluoro-ethyl-tyrosine ([18F]FET), [18F]fluoromisonidazole ([18F]FMISO) and [18F]fluorothymidine ([18F]FLT). Variables of the splitle...