Multivariate optimisation and validation of the analytical GC-FID for evaluating organic solvents in radiopharmaceutical

• Main Authors: Hassan, Hishar, Othman, Muhamad Faiz, Zakaria, Zainul Amiruddin, Ahmad Saad, Fathinul Fikri, Abdul Razak, Hairil Rashmizal
• Format: Article
• Published: Elsevier 2021
• Online Access: http://psasir.upm.edu.my/id/eprint/94303/; https://www.sciencedirect.com/science/article/pii/S1018364721002159?via%3Dihub

Objective: Analytical gas chromatography in line with a flame ionisation detector (GC-FID) method was developed and validated for evaluating organic solvents in radiopharmaceutical samples [18F]fluoroethyl-tyrosine ([18F]FET [18F] fluoromisonidazole ([18F]FMISO) and [18F] fluorothymidine ([18F]FLT)....