Microarray-based identification of differentially expressed genes associated with andrographolide derivatives-induced resistance in colon and prostate cancer cell lines

• Main Authors: Shun, Ying Quah, Charng, Choon Wong, Hui, Chyn Wong, Ho, Kok Lian, Abdul Manan, Nizar, Deb, Pran Kishore, Sagineedu, Sreenivasa Rao, Stanslas, Johnson
• Format: Article
• Published: Elsevier 2021
• Online Access: http://psasir.upm.edu.my/id/eprint/94177/; https://www.sciencedirect.com/science/article/pii/S0041008X2100209X

Chemoresistance poses a major hurdle to cancer treatments. Andrographolide-derived SRJ09 and SRJ23 were reported to exhibit potent, selective inhibitory activities against colon and prostate cancer cells, respectively. In this study, previously developed resistant colon (HCT-116rst09) and prostate (...