Analysis of expression of vitamin E-binding proteins in H2O2 induced SK-N-SH neuronal cells supplemented with α-tocopherol and tocotrienol-rich fraction

• Main Authors: Chiroma, Aishatu Ali, Khaza’ai, Huzwah, Abd. Hamid@ Abd. Razak, Roslida, Chang, Sui Kiat, Zakaria, Zainul Amiruddin, Zainal, Zaida
• Format: Article
• Language: English
• Published: Public Library of Science 2020
• Online Access: http://psasir.upm.edu.my/id/eprint/87857/1/ABSTRACT.pdf; http://psasir.upm.edu.my/id/eprint/87857/; https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0241112

Natural α-tocopherol (α-TCP), but not tocotrienol, is preferentially retained in the human body. α-Tocopherol transfer protein (α-TTP) is responsible for binding α-TCP for cellular uptake and has high affinity and specificity for α-TCP but not α-tocotrienol. The purpose of this study was to examine...