Vitamin D and Stimulates the PI3K-AKT signaling pathway in insulin resistant SK-N-SH neuronal cells

• Main Authors: Zaulkffali, Amirah Salwani, Md Razip, Nurliyana Najwa, Syed Alwi, Sharifah Sakinah, Abd Jalil, Afifah, Abd Mutalib, Mohd Sokhini, Gopalsamy, Banulata, Chang, Sui Kiat, Zainal, Zaida, Ibrahim, Nafissa Nadia, Zakaria, Zainul Amiruddin, Khaza'ai, Huzwah
• Format: Article
• Language: English
• Published: MDPI 2019
• Online Access: http://psasir.upm.edu.my/id/eprint/82729/1/Vitamin%20D%20.pdf; http://psasir.upm.edu.my/id/eprint/82729/; https://www.mdpi.com/2072-6643/11/10/2525

This study investigated the effects of vitamins D and E on an insulin-resistant model and hypothesized that this treatment would reverse the effects of Alzheimer’s disease (AD) and improves insulin signalling. An insulin-resistant model was induced in SK-N-SH neuronal cells with a treatment of 250 n...