Association of HTRA1 and ARMS2 gene polymorphisms with response to intravitreal ranibizumab among neovascular age-related macular degenerative subjects

• Main Authors: Mohamad, Nur Afiqah, Ramachandran, Vasudevan, Mohd Isa, Hazlita, Chan, Yoke Mun, Ngah, Nor Fariza, Ching, Siew Mooi, Fan, Kee Hoo, Wan Sulaiman, Wan Aliaa, Inche Mat, Liyana Najwa, Mohamed, Mohd Hazmi
• Format: Article
• Language: English
• Published: Henry Stewart Publications 2019
• Online Access: http://psasir.upm.edu.my/id/eprint/80758/1/HTRA.pdf; http://psasir.upm.edu.my/id/eprint/80758/; https://pubmed.ncbi.nlm.nih.gov/30795802/

Background: The association of HTRA1 rs11200638 and ARMS2 rs10490924 gene polymorphisms with response to intravitreal ranibizumab therapy among neovascular AMD (nAMD) subjects in Malaysia was determined in this study, followed by the expression of HTRA1 and ARMS2 genes. Results: Both single nucleoti...