Overexpression of acetyl-CoA carboxylase in Aspergillus terreus to increase lovastatin production
The present work describes the application of homologous recombination techniques in a wild-type Aspergillus terreus (ATCC 20542) strain to increase the flow of precursors towards the lovastatin biosynthesis pathway. A new strain was generated to overexpress acetyl-CoA carboxylase (ACCase) by replac...
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Main Authors: | Hasan, Hanan, Abd Rahim, Muhammad Hafiz, Campbell, Leona, Carter, Dee, Abbas, Ali, Montoya, Alejandro |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018
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Online Access: | http://psasir.upm.edu.my/id/eprint/75182/1/Overexpression.pdf http://psasir.upm.edu.my/id/eprint/75182/ https://www.sciencedirect.com/science/article/abs/pii/S1871678417306763?via%3Dihub |
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