Development of nanoemulsion for efficient brain parental delivery of cefuroxime: designs,characterizations,and pharmacokinetics

• Main Authors: Harun, Siti Norhawani, Amin Nordin, Syafinaz, Abd Gani, Siti Salwa, Shamsuddin, Ahmad Fuad, Basri, Mahiran, Basri, Hamidon
• Format: Article
• Language: English
• Published: Dove Medical Press 2018
• Online Access: http://psasir.upm.edu.my/id/eprint/72266/1/development-of-nanosystem-efficient-utilizing-emulsion-for-b_042618.pdf; http://psasir.upm.edu.my/id/eprint/72266/; https://www.dovepress.com/development-of-nanoemulsion-for-efficient-brain-parenteral-delivery-of-peer-reviewed-article-IJN

Background and aim: Drugs that are effective against diseases in the central nervous system and reach the brain via blood must pass through the blood–brain barrier (BBB), a unique interface that protects against potential harmful molecules. This presents a major challenge in neuro-drug delivery. Thi...