Suppression of PGE2 production via disruption of MAPK phosphorylation by unsymmetrical dicarbonyl curcumin derivatives

• Main Authors: Aluwi, Mohd Fadhlizil Fasihi Mohd, Rullah, Kamal, Haque, Md. Areeful, Yamin, Bohari M., Ahmad, Waqas, Amjad, Muhammad Wahab, Leong, Sze Wei, Fahmizar, Nurul Amira, Jalil, Juriyati, Abas, Faridah, Ismail, Nor Hadiani, Jantan, Ibrahim, Kok, Wai Lam
• Format: Article
• Language: English
• Published: Springer 2017
• Online Access: http://psasir.upm.edu.my/id/eprint/63336/1/Suppression%20of%20PGE2%20production%20via%20disruption%20of%20MAPK%20phosphorylation%20by%20unsymmetrical%20dicarbonyl%20curcumin%20derivatives.pdf; http://psasir.upm.edu.my/id/eprint/63336/; https://link.springer.com/article/10.1007/s00044-017-2025-4

Curcumin is an important molecule found in turmeric plants and has been reported to exhibit some profound anti-inflammatory activities by interacting with several important molecular targets found in the mitogen-activated protein kinase and NF-κβ pathways. As part of our continuing effort to search...