In vitro evaluation of a novel pH sensitive drug delivery system based cockle shell-derived aragonite nanoparticles against osteosarcoma

• Main Authors: Fu, Wenliang, Mohd Noor, Mohd Hezmee, Mohamad Yusof, Loqman, Tengku Ibrahim, Tengku Azmi, Keong, Yeap Swee, Jaji, Alhaji Zubair, Abu Bakar @ Zakaria, Md Zuki
• Format: Article
• Language: English
• Published: Taylor & Francis 2017
• Online Access: http://psasir.upm.edu.my/id/eprint/62138/1/In%20vitro%20evaluation%20of%20a%20novel%20pH%20sensitive%20drug%20delivery%20system%20based%20cockle%20shell-derived%20aragonite%20nanoparticles%20against%20osteosarcoma.pdf; http://psasir.upm.edu.my/id/eprint/62138/; https://www.tandfonline.com/doi/full/10.1080/17458080.2017.1287965

Background: Osteosarcoma (OS) is a highly malignant primary bone cancer. Severe side effects and multidrug resistance are obstacles faced with chemotherapy against OS. With the hope to overcome the obstacles of the conventional chemotherapy, various targeted drug delivery systems using nanotechnolog...