In vivo evaluation of anticancer efficacy of drug loaded cockle shell‐derived aragonite nanoparticles

• Main Authors: Fu, Wenliang, P Rameli, Mohd Adha, Tengku Ibrahim, Tengku Azmi, Mohd Noor, Mohd Hezmee, Mohamad Yusof, Loqman, Abu Bakar @ Zakaria, Md Zuki
• Format: Article
• Language: English
• Published: John Wiley & Sons 2019
• Online Access: http://psasir.upm.edu.my/id/eprint/80226/1/In%20vivo%20evaluation%20of%20anticancer%20efficacy%20of%20drug%20loaded%20cockle%20shell%E2%80%90derived%20aragonite%20nanoparticles.pdf; http://psasir.upm.edu.my/id/eprint/80226/; https://onlinelibrary.wiley.com/doi/pdf/10.1002/jbm.b.34282

Doxorubicin (DOX) is an effective and commonly used anthracycline anticancer drug for the treatment of osteosarcoma (OS). However, its antitumor effect is hampered by the nonspecific distribution and significant adverse effects. Nanoparticles based drug delivery systems are promising approaches to m...