A simple add-and display method for immobilisation of cancer drug on his-tagged virus-like nanoparticles for controlled drug delivery
pH-responsive virus-like nanoparticles (VLNPs) hold promising potential as drug delivery systems for cancer therapy. In the present study, hepatitis B virus (HBV) VLNPs harbouring His-tags were used to display doxorubicin (DOX) via nitrilotriacetic acid (NTA) conjugation. The His-tags served as pH-r...
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Main Authors: | Biabanikhankahdani, Roya, Bayat, Saadi, Ho, Kok Lian, Mohammed Alitheen, Noorjahan Banu, Tan, Wen Siang |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2017
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Online Access: | http://psasir.upm.edu.my/id/eprint/60732/1/A%20simple%20add-and%20display%20method%20for%20immobilisation%20of%20cancer%20drug%20on%20his-tagged%20virus-like%20nanoparticles%20for%20controlled%20drug%20delivery.pdf http://psasir.upm.edu.my/id/eprint/60732/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5509718/pdf/41598_2017_Article_5525.pdf |
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