Methanolic extract of Clinacanthus nutans exerts antinociceptive activity via the opioid/nitric oxide-mediated, but cGMP-independent, pathways

• Main Authors: Abdul Rahim, Mohammad Hafiz, Zakaria, Zainul Amiruddin, Mohd Sani, Mohd Hijaz, Omar, Maizatul Hasyima, Yakob, Yusnita, Singh, Manraj, Cheema, Ching, Siew Mooi, Ahmad, Zuraini, Abdul Kadir, Arifah
• 格式: Article
• 语言: English
• 出版: Hindawi Publishing Corporation 2016
• 在线阅读: http://psasir.upm.edu.my/id/eprint/54798/1/Methanolic%20extract%20of%20Clinacanthus%20nutans%20exerts%20antinociceptive%20activity.pdf; http://psasir.upm.edu.my/id/eprint/54798/; https://www.hindawi.com/journals/ecam/2016/1494981/abs/

The objectives of the present study were to determine the mechanisms of antinociceptive effect of methanol extract of Clinacanthus nutans (Acanthaceae) leaves (MECN) using various animal nociceptive models. The antinociceptive activity of orally administered 10% DMSO, 100 mg/kg acetylsalicylic acid...