Virulence, host-selective toxin production, and development of three Cochliobolus phytopathogens lacking the Sfp-type 4′-phosphopantetheinyl transferase Ppt1

• Main Authors: Mohd Zainudin, Nur Ain Izzati, Condon, Bradford, De Bruyne, Lieselotte, Van Poucke, Christof, Bi, Qing, Li, Wei, Höfte, Monica, Turgeon, B. Gillian
• Format: Article
• Language: English
• Published: APS Press 2015
• Online Access: http://psasir.upm.edu.my/id/eprint/52019/1/Virulence%2C%20host-selective%20toxin%20production%2C%20and%20development%20of%20three%20Cochliobolus%20phytopathogens%20lacking%20the%20Sfp-type%204%E2%80%B2-phosphopantetheinyl%20transferase%20Ppt1.pdf; http://psasir.upm.edu.my/id/eprint/52019/; http://apsjournals.apsnet.org/doi/abs/10.1094/MPMI-03-15-0068-R

The Sfp-type 4′-phosphopantetheinyl transferase Ppt1 is required for activation of nonribosomal peptide synthetases, including α-aminoadipate reductase (AAR) for lysine biosynthesis and polyketide synthases, enzymes that biosynthesize peptide and polyketide secondary metabolites, respectively. Delet...