Virulence, host-selective toxin production, and development of three Cochliobolus phytopathogens lacking the sfp-type 4'-phosphopantetheinyl transferase ppt1

• Main Authors: Mohd Zainudin, Nur Ain Izzati, Condon, Bradford, De Bruyne, Lieselotte, Poucke, Christof Van, Qing, Bi, Wei, Li, Hofte, Monica, Turgeon, B. Gillian
• Format: Article
• Language: English
• Published: American Phytopathological Society 2015
• Online Access: http://psasir.upm.edu.my/id/eprint/46865/1/Virulence%2C%20host-selective%20toxin%20production%2C%20and%20development%20of%20three%20Cochliobolus%20phytopathogens%20lacking%20the%20Sfp-type%204%27-phosphopantetheinyl%20transferase%20Ppt1.pdf; http://psasir.upm.edu.my/id/eprint/46865/; http://apsjournals.apsnet.org/loi/mpmi

The Sfp-type 4′-phosphopantetheinyl transferase Ppt1 is required for activation of nonribosomal peptide synthetases, including α-aminoadipate reductase (AAR) for lysine biosynthesis and polyketide synthases, enzymes that biosynthesize peptide and polyketide secondary metabolites, respectively. Delet...