The mazef toxin-antitoxin system as an attractive target in clinical isolates of Enterococcus faecium and Enterococcus faecalis

• Main Authors: Soheili, Sara, Ghafourian, Sobhan, Sekawi, Zamberi, Neela, Vasantha Kumari, Sadeghifard, Nourkhoda, Taherikalani, Morovat, Khosravi, Afra, Ramli, Ramliza, Awang Hamat, Rukman
• Format: Article
• Language: English
• Published: Dove Medical Press 2015
• Online Access: http://psasir.upm.edu.my/id/eprint/46648/1/The%20mazef%20toxin-antitoxin%20system%20as%20an%20attractive%20target%20in%20clinical%20isolates%20of%20Enterococcus%20faecium%20and%20Enterococcus%20faecalis.pdf; http://psasir.upm.edu.my/id/eprint/46648/; http://www.dovepress.com/drug-design-development-and-therapy-journal

The toxin-antitoxin (TA) system is a regulatory system where two sets of genes encode the toxin and its corresponding antitoxin. In this study, the prevalence of TA systems in independently isolated clinical isolates of Enterococcus faecium and Enterococcus faecalis was determined, the dominant TA s...