Tetraprenyltoluquinone, an anticancer compound from Garcinia cowa Roxb induce cell cycle arrest on H460 non small lung cancer cell line

• Main Authors: Wahyuni, Fatma Sri, Lim, Siang Hui, Stanslas, Johnson, Lajis, Nordin, Hamidi, Dachriyanus
• Format: Article
• Language: English
• Published: Global Research Online Publishing House 2015
• Online Access: http://psasir.upm.edu.my/id/eprint/46511/1/Tetraprenyltoluquinone%2C%20an%20anticancer%20compound%20from%20Garcinia%20cowa%20Roxb%20induce%20cell%20cycle%20arrest%20on%20h460%20non%20small%20lung%20cancer%20cell%20line_New.pdf; http://psasir.upm.edu.my/id/eprint/46511/; https://www.globalresearchonline.net/pharmajournal/vol32iss2.aspx

Tetraprenyltoluquinone (TPTQ), isolated compound from stem bark of Garcinia cowa Roxb showed selective cytotoxicity towards H460 lung cancer cell line. We further investigated the ability of this compound in inducing cell cycle arrest by flow cytometry. Cell cycle analysis revealed that TPTQ caused...