Optimization of fish gelatin-alginate-genipin as encapsulating matrices for probiotic application using FCCD-RSM

The optimal composition of fish gelatin-alginate-genipin to encapsulate Bifidobacterium pseudocatenulatum G4 was studied. The Face Central Composition Design-Response Surface Methodology (FCCD-RSM) was employed to determine the optimal ration of the matrices in order to obtain high in encapsulation...

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Bibliographic Details
Main Authors: Abdul Khalil, Khalilah, Mustafa, Shuhaimi, Mohamad, Rosfarizan, Ariff, Arbakariya, Abdul Manap, Yazid
Format: Conference or Workshop Item
Language:English
Published: IEEE 2012
Online Access:http://psasir.upm.edu.my/id/eprint/39561/1/Optimization%20of%20fish%20gelatin-alginate-genipin%20as%20encapsulating%20matrices%20for%20probiotic%20application%20using%20FCCD-RSM.pdf
http://psasir.upm.edu.my/id/eprint/39561/
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Summary:The optimal composition of fish gelatin-alginate-genipin to encapsulate Bifidobacterium pseudocatenulatum G4 was studied. The Face Central Composition Design-Response Surface Methodology (FCCD-RSM) was employed to determine the optimal ration of the matrices in order to obtain high in encapsulation yield (%) and beads strength. Results indicated that optimized matrices could increase the entrapped viable cells and beads strength. The optimal combination of encapsulating matrices was found to be 12.57 % for fish gelatin combined with 5 % alginate and 19.1 mM genipin. Verification experiment confirmed the prediction with low value error and gave indication a good performance prognosis of the optimal formulation.