Genetic markers in a Malaysian population: variants of uridine monophosphate kinase (UMPK), phosphoglycolate phosphatase (PGP) and pancreatic amylase (AMY₂)

• Main Authors: K. H., Zarinah, Abdullah, F., Tan, S. G.
• Format: Article
• Language: English
• Published: Informa Healthcare 1984
• Online Access: http://psasir.upm.edu.my/id/eprint/38431/1/aar%206%20Genetic%20markers%20in%20a%20Malaysian%20population%20variants%20of%20uridine%20monophosphate%20kinase%20%28UMPK%29%2C%20phosphoglycolate%20phosphatase%20%28PGP%29%20and%20pancreatic%20amylase%20%28AMY2%29.pdf; http://psasir.upm.edu.my/id/eprint/38431/

Three genetic markers, red-cell UMPK, PGP and serum AMY₂ were investigated in Malaysians of Malay, Chinese and Indian ancestries using starch-gel and agarose-gel electrophoresis. UMPK was found to be polymorphic in all three races. Variants were observed for PGP in Malays; in Indians it is a polymorphic marker whereas it is monomorphic in Chinese. AMY₂ was polymorphic only in Indians. The UMPK¹ frequencies in Malays, Chinese and Indians, respectively, are 0.851, 0.880 and 0.942. The PGP¹ frequencies are 0.991, 1.000, 0.962, and the AMY½frequencies are 1.000, 1.000 and 0.983.