Prioritization of natural extracts by LC-MS-PCA for the identification of new photosensitizers for photodynamic therapy

• Main Authors: Samat, Norazwana, Tan, Pei Jean, Shaari, Khozirah, Abas, Faridah, Lee, Hong Boon
• Format: Article
• Language: English
• Published: American Chemical Society 2014
• Online Access: http://psasir.upm.edu.my/id/eprint/35056/1/Prioritization%20of%20natural%20extracts%20by%20LC.pdf; http://psasir.upm.edu.my/id/eprint/35056/; http://pubs.acs.org/doi/abs/10.1021/ac403709a

Photodynamic therapy (PDT) is an alternative treatment for cancer that involves administration of a photosensitive drug or photosensitizer that localizes at the tumor tissue followed by in situ excitation at an appropriate wavelength of light. Tumour tissues are then killed by cytotoxic reactive oxy...