Anti-hyperalgesic effect of a benzilidine-cyclohexanone analogue on a mouse model of chronic constriction injury-induced neuropathic pain: participation of the κ-opioid receptor and KATP

• Main Authors: Lee, Ming Tatt, Khalivulla, Shaik Ibrahim, Akhtar, Muhammad Nadeem, Lajis, Nordin, Perimal, Enoch Kumar, Omar Farouk, Ahmad Akira, Israf Ali, Daud Ahmad, Sulaiman, Mohd Roslan
• Format: Article
• Published: Elsevier 2013
• Online Access: http://psasir.upm.edu.my/id/eprint/29708/

The present study investigated the analgesic effect of a novel synthetic cyclohexanone derivative, 2,6-bis-4-(hydroxyl-3-methoxybenzilidine)-cyclohexanone or BHMC in a mouse model of chronic constriction injury-induced neuropathic pain. It was demonstrated that intraperitoneal administration of BHMC...