Experimental characterization of the chronic constriction injury-induced neuropathic pain model in mice

• Main Authors: Gopalsamy, Banulata, Sambasevam, Yogesvari, Zulazmi, Nurul Atiqah, Chia, Jasmine Siew Min, Farouk, Ahmad Akira Omar, Sulaiman, Mohd Roslan, Tengku Mohamad, Tengku Azam Shah, Perimal, Enoch Kumar
• Format: Article
• Published: Springer 2019
• Online Access: http://psasir.upm.edu.my/id/eprint/79797/; https://link.springer.com/article/10.1007/s11064-019-02850-0

Number of ligations made in the chronic constriction injury (CCI) neuropathic pain model has raised serious concerns. We compared behavioural responses, nerve morphology and expression of pain marker, c-fos among CCI models developed with one, two, three and four ligations. The numbers of ligation(s...