Effects of medium and culture conditions on folate production by Streptococcus thermophilus BAA-250.
The present study was conducted to investigate the effects of culture conditions on folate production by Streptococcus thermophilus BAA-250. Lactose (3g/L) and yeast extract (20g/L) were found to be the more suitable carbon and nitrogen sources for folate production by S. thermophilus BAA-250....
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English English |
| Published: |
2013
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| Online Access: | http://psasir.upm.edu.my/id/eprint/28123/1/Effects%20of%20medium%20and%20culture%20conditions%20on%20folate%20production%20by%20Streptococcus%20thermophilus%20BAA.pdf http://psasir.upm.edu.my/id/eprint/28123/ http://researchinbiotechnology.com/issue/view/21 |
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| Summary: | The present study was conducted to investigate the effects of culture conditions on
folate production by Streptococcus thermophilus BAA-250. Lactose (3g/L) and yeast extract
(20g/L) were found to be the more suitable carbon and nitrogen sources for folate production
by S. thermophilus BAA-250. para-aminobenzoic acid (pABA) higher than 1 µM had no
significant effect on folate biosynthesis. The optimum pH for folate production was shown
to be 7.0 with a folate yield and productivity of 54.53 (µg/L) and 2.27 (µg/L.h), respectively.
Optimum folate production obtained in the presence of lactose and yeast extract in a
controlled pH of 7 during batch fermentation in bioreactor. Kinetic studies indicated that
folate production by S. thermophilus is growth-associated process. |
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