Optimization of an induction strategy for improving interferon-α2b production in the periplasm of Escherichia coli using response surface methodology
Induction strategies for the periplasmic production of recombinant human IFN-alpha2b (interferon-alpha2b) by recombinant Escherichia coli Rosetta-gami 2(DE3) were optimized in shake-flask cultures using response surface methodology based on the central composite design. The factors included in the p...
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Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
Portland Press
2010
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Online Access: | http://psasir.upm.edu.my/id/eprint/15962/1/Optimization%20of%20an%20induction%20strategy%20for%20improving%20interferon.pdf http://psasir.upm.edu.my/id/eprint/15962/ |
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