Enhancement of monoclonal antibody productivity by promoting active hypothermic growth in hybridoma cells

BACKGROUND: Many reports have suggested that mild hypothermic culture conditions improve the specific monoclonal antibody (mAb) productivity of mammalian cells. The effect of active hypothermic growth on the mAb productivity of the hybridoma C2E7 was investigated. Hybridoma growth under hypothermic...

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Bibliographic Details
Main Authors: Chong, Sun Li, Mou, Duen Gang, Lim, Saw Hoon, Ali, Abdul Manaf, Tey, Beng Ti
Format: Article
Language:English
Published: Society of Chemical Industry 2009
Online Access:http://psasir.upm.edu.my/id/eprint/14517/1/Enhancement%20of%20monoclonal%20antibody%20productivity%20by%20promoting%20active%20hypothermic%20growth%20in%20hybridoma%20cells.pdf
http://psasir.upm.edu.my/id/eprint/14517/
https://onlinelibrary.wiley.com/doi/abs/10.1002/jctb.2228
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