In vitro cytotoxicity assessment of ruxolitinib on oligodendrocyte precursor cell and neural stem/progenitor cell populations
JAK-STAT signaling cascade has emerged as an ideal target for the treatment of myeloproliferative diseases, autoimmune diseases, and neurological disorders. Ruxolitinib (Rux), is an orally bioavailable, potent and selective Janus-associated kinase (JAK) inhibitor, proven to be effective to target...
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Main Authors: | Lim, Cheng-Wei, Hamanaka, Gen, Liang, Anna C., Chan, Su Jing, Ling, King-Hwa, Lo, Eng H., Arai, Ken, Cheah, Pike See |
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Format: | Article |
Language: | English |
Published: |
Elsevier
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Online Access: | http://psasir.upm.edu.my/id/eprint/113251/1/113251.pdf http://psasir.upm.edu.my/id/eprint/113251/ https://www.sciencedirect.com/science/article/pii/S0161813X24001001 |
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