Metabolomics combined with chemometric analysis to identify α-glucosidase inhibitors in Phaleria macrocarpa fruit extracts and its molecular docking simulation

• 主要な著者: Easmin, Sabina, Sarker, Zaidul Islam, Khatib, Alfi, Ferdosh, Sahena, Jaffri, Juliana, Uddin, ABM Helal, Murugesu, Suganya, Balan, Tavamani, Perumal, Vikneswari
• フォーマット: 論文
• 出版事項: Elsevier 2024
• オンライン･アクセス: http://psasir.upm.edu.my/id/eprint/112805/; https://www.sciencedirect.com/science/article/abs/pii/S0254629924001820?via%3Dihub

Phaleria macrocarpa is a medicinal plant widely available in Malaysia. The plant parts have been traditionally used as an antidiabetic remedy. This study aimed to identify the putative inhibitors of the α-glucosidase enzyme from P. macrocarpa using a gas chromatography-mass spectrometry (GC–MS)-base...