Evaluation of lentiviral based gene delivery system in adherent and suspension in vitro cell models

• Main Authors: Mohd Idris, Izyan, Nordin, Fazlina, Muhamad, Nur Jannaim, Idris, Siti Zuleha, Tye, Gee Jun, Wan Kamarul Zaman, Wan Safwani, Ng, Min Hwei
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2024
• Online Access: http://psasir.upm.edu.my/id/eprint/112451/1/112451.pdf; http://psasir.upm.edu.my/id/eprint/112451/; https://www.ukm.my/jsm/pdf_files/SM-PDF-53-3-2024/6.pdf

Lentiviruses are a highly robust gene delivery system capable of in vitro and in vivo gene transfer into multiple cell types. Recent fourth-generation lentiviral systems have been designed for enhanced safety, however, the increased recombination events required to produce infective lentiviral parti...