Evaluation of lentiviral based gene delivery system in adherent and suspension in vitro cell models

• Main Authors: Izyan Mohd Idris,, Fazlina Nordin,, Nur Jannaim Muhamad,, Siti Zuleha Idris,, Gee, Jun Tye, Wan Safwani Wan Kamarul Zaman,, Min, Hwei Ng
• Format: Article
• Language: English
• Published: Penerbit Universiti Kebangsaan Malaysia 2024
• Online Access: http://journalarticle.ukm.my/23737/1/SMT%206.pdf; http://journalarticle.ukm.my/23737/; https://www.ukm.my/jsm/english_journals/vol53num3_2024/contentsVol53num3_2024.html

Lentiviruses are a highly robust gene delivery system capable of in vitro and in vivo gene transfer into multiple cell types. Recent fourth-generation lentiviral systems have been designed for enhanced safety, however, the increased recombination events required to produce infective lentiviral parti...