Lignosus rhinocerotis extract ameliorates airway inflammation and remodelling via attenuation of TGF-β1 and Activin A in a prolonged induced allergic asthma model

Allergic asthma is associated with chronic airway inflammation and progressive airway remodelling. The sclerotium of Lignosus rhinocerotis (Cooke) Ryvarden (Tiger Milk mushroom) is used traditionally to treat various illnesses, including asthma in Southeast Asia. This study was carried out to evalua...

Full description

Saved in:

Bibliographic Details
Main Authors:	Muhamad, Siti-Aminah, Safuan, Sabreena, Stanslas, Johnson, Wan Ahmad, Wan Amir Nizam, Mohd-Rosdan Bushra, Solehah, Bushra Nurul, Asma
Format:	Article
Published:	Springer Science and Business Media LLC 2023
Online Access:	http://psasir.upm.edu.my/id/eprint/110163/ https://www.nature.com/articles/s41598-023-45640-z?error=cookies_not_supported&code=3a4d3b5a-f081-4839-a9db-4011ed4524c8
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

The effects of tiger milk mushroom (lignosus rhinocerotis) on airway inflammation in murine models of allergic asthma
by: Muhamad, Siti Aminah
Published: (2020)

Lignosus rhinocerotis Cooke Ryvarden ameliorates airway inflammation, mucus hypersecretion and airway hyperresponsiveness in a murine model of asthma
by: Johnathan, Malagobadan, et al.
Published: (2021)

Does Inhalation of Virgin Coconut Oil Accelerate Reversal of Airway Remodelling in an Allergic Model of Asthma?
by: Kamalaldin, N. A., et al.
Published: (2017)

Evaluation of the male and female fertility and teratogenic effects of Lignosus rhinocerotis (Cooke) Ryvarden in rats
by: Zati Bayani Hamzah,, et al.
Published: (2022)

Airway relaxation effects of water-soluble sclerotial extract from Lignosus rhinocerotis
by: Lee, Mei Kee, et al.
Published: (2018)

A synthetic curcuminoid analogue, 2,6-Bis-4-(Hydroxyl-3-Methoxybenzylidine)-Cyclohexanone (BHMC) ameliorates acute airway inflammation of allergic asthma in ovalbumin-sensitized mice
by: Tham, Chau Ling, et al.
Published: (2021)

A semisynthetic diterpenoid lactone inhibits NF-kB signalling to ameliorate inflammation and airway hyperresponsiveness in a mouse asthma model
by: Lim, J. C. W., et al.
Published: (2016)

Phytochemical profiles, anti-asthmatic and immunomodulatory effects of lignosus rhinocerus in airway inflammation model
by: Malagobadan, Johnathan A/L
Published: (2016)

Genome-based Proteomic Analysis of Lignosus rhinocerotis (Cooke) Ryvarden Sclerotium
by: Yap, H.Y.Y., et al.
Published: (2015)

Airway remodeling blockade with an orally active geranyl acetophenone
by: Lee, Yu Zhao
Published: (2017)

Indoor air pollutants in schools and their relationship with airway inflammation, respiratory and allergic symptoms among school children in Hulu Langat, Malaysia
by: Mohd Isa, Khairul Nizam
Published: (2021)

Identification and in vitro evaluation of lipids from sclerotia of lignosus rhinocerotis for antioxidant and anti-neuroinflammatory activities
by: Nallathamby, Neeranjini, et al.
Published: (2016)

Gold nanoparticles biosynthesized using Lignosus rhinocerotis extracts: comparative evaluation of biostatic and cytotoxicity effects
by: Ahmad Yasser Hamdi Nor Azlan,, et al.
Published: (2020)

Fibrinolytic activities of a medicinal mushroom: Lignosus rhinocerotis (Cooke) ryvarden / Kho Tieng Tieng
by: Kho, Tieng Tieng
Published: (2014)

Neuroprotective and neuritogenic activities of Lignosus rhinocerotis (COOKE) ryvarden / Priscilla Ann a/p Moknasing @ John
by: Moknasing, Priscilla Ann
Published: (2015)

TGF-ß1 signalling, connecting aberrant inflammation and colorectal tumorigenesis
by: Paterson, I.C., et al.
Published: (2012)

PI3K/mTORC2 regulates TGF-β/Activin signalling by modulating Smad2/3 activity via linker phosphorylation
by: Yu, J.S.L., et al.
Published: (2015)

Standardised Andrographis paniculata Burm. Nees extracts and andrographolide prevent airway inflammation in house dust mite and diisocyanate- induced asthma models
by: Sulaiman, Ibrahim
Published: (2018)

2,4,6,-trihydroxy-3-geranylacetophenone (tHGA) suppresses chronic allergic airway inflammation in ovalbumin-sensitized mice via intraperitoneal route
by: Ismail, Norazren, et al.
Published: (2019)

Toxicological and anti-inflammatory effects of lignosus rhinocerotis cooke ryvarden (tiger milk mushroom) / Lee Sook Shien
by: Lee, Sook Shien
Published: (2016)

An Andrographis paniculata Burm. Nees extract standardized for three main Andrographolides prevents house dust mite-induced airway inflammation, remodeling, and hyperreactivity by regulating Th1/Th2 gene expression in mice
by: Sulaiman, Ibrahim, et al.
Published: (2024)

Cytoprotective effects of the tiger's milk mushroom lignosus rhinocerotis (Agaricomycetes) sclerotia against oxidative stress in PC12 cells
by: Tan, Yong Hui, et al.
Published: (2022)

In vivo teratogenecity and anti-allergic of lignosus rhinoceros in an asthmatic robert model and their possible bioactive constituents
by: Abdullah, Nurul Asma
Published: (2016)

Activin A: its role and involvement in inflammatory diseases
by: Tie, Tung Hing, et al.
Published: (2015)

Analysis of neurite outgrowth activity of aqueous extract of Lignosus Rhinocerotis (COOKE) ryvarden in pc-12 cells / Eik Lee Fang
by: Eik, Lee Fang
Published: (2015)

$Dye decolorisation capacity of lignosus rhinocerotis (cooke) ryvarden dialysed fraction and its expression of novel recombinant laccase in pichia pastoris$

Dye decolorisation capacity of lignosus rhinocerotis (cooke) ryvarden dialysed fraction and its expression of novel recombinant laccase in pichia pastoris
by: Lee, Siew Wei, et al.
Published: (2022)