Sodium alginate encapsulated iron oxide decorated with thymoquinone nanocomposite induces apoptosis in human breast cancer cells via PI3K-Akt-mTOR pathway

• Main Authors: Alzahrani, Badr, Elderdery, Abozer Y., Alsrhani, Abdullah, Alzerwi, Nasser A.N., Althobiti, Maryam Musleh, Elkhalifa, Ahmed M.E., Rayzah, Musaed, Idrees, Bandar, Kumar, Suresh S., Mok, Pooi Ling
• Format: Article
• Published: Elsevier 2023
• Online Access: http://psasir.upm.edu.my/id/eprint/109496/; https://linkinghub.elsevier.com/retrieve/pii/S0141813023019487

The present study investigated the cytotoxicity and proapoptotic properties of iron oxide-sodium-alginate-thymoquinone nanocomposites against breast cancer MDA-MB-231 cells in vitro and in silico. This study used chemical synthesis to formulate the nanocomposite. Electron microscopies such as scanni...