Enhanced apoptotic activity of Pluronic F127 polymer-encapsulated chlorogenic acid nanoparticles through the PI3K/Akt/mTOR signaling pathway in liver cancer cells and in vivo toxicity studies in zebrafish

• Main Authors: Alanazi, Fehaid, Elderdery, Abozer Y., Alzahrani, Badr, Alzerwi, Nasser A. N., Althobiti, Maryam Musleh, Rayzah, Musaed, Alanazi, Abdulaziz Suailem, Kuriri, Fahd A., Idrees, Bandar, Alenazy, Fawaz O., Alsultan, Afnan, Rayzah, Fares, Baksh, Yaser, Subbiah, Suresh Kumar, Mok, Pooi Ling
• Format: Article
• Published: De Gruyter 2023
• Online Access: http://psasir.upm.edu.my/id/eprint/107684/; https://www.degruyter.com/document/doi/10.1515/epoly-2023-0053/html

In this study, chlorogenic acid nanoparticles encapsulated in Pluronic F127 polymer were synthesized and characterized to determine if they could treat human liver cancer. The nanoparticles were synthesized using standard procedures and characterized using physical and biological techniques such as...