Germinated brown rice extract reduces brain lipid peroxidation and Aβ levels via regulations of BACE1, RAGE, IDE and LRP1 expressions in high fat/cholesterol diet-fed rats

• Main Authors: Azmi, Nur Hanisah, Ismail, Norsharina, Imam, Mustapha Umar, Ooi, Der Jiun, Yida, Zhang, Abdul Aziz, Ahmad Hazim, Mohamad Rosdi, Mohamad Norisham
• Format: Article
• Published: Elsevier 2023
• Online Access: http://psasir.upm.edu.my/id/eprint/108106/; https://linkinghub.elsevier.com/retrieve/pii/S1756464623001871

A strong association presents between excessive amyloid-β (Aβ) buildup and oxidative stress with Alzheimer’s disease (AD). In view of the multifaceted neuroprotective effects of some dietary elements, the beneficial effect of germinated brown rice was investigated using a high fat/cholesterol diet (...