Endolysins against Streptococci as an antibiotic alternative

• Main Authors: Wong, Kuan Yee, Megat Mazhar Khair, Megat Hamzah, Song, Adelene Ai Lian, Masarudin, Mas Jaffri, Chong, Chou Min, Lian, Lionel Aun In, Yee, Michelle Mun Teo
• Format: Article
• Published: Frontiers Research Foundation 2022
• Online Access: http://psasir.upm.edu.my/id/eprint/101248/; https://www.frontiersin.org/articles/10.3389/fmicb.2022.935145/full

Multi-drug resistance has called for a race to uncover alternatives to existing antibiotics. Phage therapy is one of the explored alternatives, including the use of endolysins, which are phage-encoded peptidoglycan hydrolases responsible for bacterial lysis. Endolysins have been extensively research...