Reflexin A, a new indole alkaloid from Rauvolfia reflexa induces apoptosis against colon cancer cells

• Main Authors: Fadaeinasab, M., Karimian, H., Omar, H., Taha, H., khorasani, A., Banisalam, B., Aziz Ketuly, K., Abdullah, Z.
• Format: Article
• Language: English
• Published: 2020

One new indole alkaloid, reflexin A (1), and two known indoles, macusine B (2) and vinorine (3), were isolated from the bark of Rauvolfia reflexa. Their structures were elucidated by 1D and 2D NMR, UV, IR, and MS spectroscopic analyses. Compound 1 displayed anticancer activity against HCT-116 colon...